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過去の講演会
第564回川崎医学会講演会
| 日 時 | 令和7年5月27日（火）16:00～17:00 |
| 場 所 | 医科大学図書館小講堂 |
| 座 長 | 青山 裕美 |
| 演 題 | 「Endotypes and variants of atopic dermatitis: a molecular perspective」 |
| 演 者 | Kilian Eyerich MD Full Professor and Medical Director, Department of Dermatology, Medical Center University of Freiburg |
The clinical phenotype of atopic dermatitis (AD) is highly heterogeneous regarding age of onset, associated comorbidities, dynamics and triggers, and predilection areas. This heterogeneity is, however, not strongly correlated to the therapeutic response to specific therapies such as biologics or smart molecules. Thus, it is currently impossible to predict the therapeutic response at an individual patient's level in AD, as much as it is impossible to estimate the risk to develop a comorbidity or development of adverse events to a therapeutic intervention. At the same time, technological advances such as spatial and/or single cell transcriptome or proteome analysis allow a more and more detailled insight into pathogenic molecular events in AD. This presentation will focus at proposed molecular endotypes of AD according to different data layers such as transcriptome, microbiome, proteome, or lipidome analysis. It will highlight the broad absence of validated data, as well as the need to integrate different data layers into molecular modelling to finally achieve clinically meaningfull results and potentially a new disease classification
詳細はこちら
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